Cell Death Signaling in Cancer Biology and Treatment PDF
By:Daniel Johnson
Published on 2012-11-19 by Springer Science & Business Media
A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.
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Book ID of Cell Death Signaling in Cancer Biology and Treatment's Books is XRbr1o2gb6EC, Book which was written byDaniel Johnsonhave ETAG "eu0i4kjXdmU"
Book which was published by Springer Science & Business Media since 2012-11-19 have ISBNs, ISBN 13 Code is 9781461458470 and ISBN 10 Code is 1461458471
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Book which have "408 Pages" is Printed at BOOK under CategoryScience
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